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1.
PLoS One ; 19(5): e0298901, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38743722

RESUMO

The application of visual art and other extracurricular activities to children's sustainable development is predominantly discussed in Western countries. Consequently, non-Western society could not cherish the benefit of visual art on their children's cognitive and non-cognitive skill development due to a lack of evidence that would revive the community, educators, and policy-makers' impressions about visual art activities, in addition to its amusement use. Thus, the present study adopted a cross-sectional study comprised of a large-scale survey (N = 1624) taken from the southwest part of China to assess the impact of out-of-school visual art activities on children's academic attainment across economically advantaged and disadvantaged children. Astonishingly, the study's findings shed light on current Chinese parents' dedication to purchasing out-of-school activities regardless of their social class difference; notwithstanding, lower-class parents ought to learn that spending time with their children during their activities is more beneficial. The study's implication calls for curriculum policy reform involving aesthetic education and expanding community youth centers for different extracurricular activities.


Assuntos
Desempenho Acadêmico , Arte , Instituições Acadêmicas , Classe Social , Humanos , Masculino , Feminino , Criança , Estudos Transversais , China , Adolescente
2.
BMC Psychol ; 12(1): 90, 2024 Feb 22.
Artigo em Inglês | MEDLINE | ID: mdl-38389094

RESUMO

Using the event-related potentials (ERPs) technique, this study successively presented names (in either a supra- or subthreshold manner) and emotional words to examine how self-relevant cue (self-name) affects emotional word processing in word class judgment task (to determine whether an emotional word is a noun or adjective) and valence judgment task (to determine whether an emotional word is positive or negative). At the suprathreshold condition, self-relevant positive words elicited a more significant Early posterior negativity (EPN) than negative words only in the valence judgment task. In contrast, at the subthreshold condition, self-relevant negative words elicited an enhanced Late positive potential (LPP) than positive words only in the word class judgment task. These results indicate that self-relevant cue affects emotional word processing at both suprathreshold and subthreshold conditions; nevertheless, the effect manifests as self-positive bias at the suprathreshold condition and self-negative bias at the subthreshold condition. The experimental task modulates these dynamics.


Assuntos
Eletroencefalografia , Processamento de Texto , Humanos , Emoções , Potenciais Evocados , Cognição
3.
Sci Rep ; 14(1): 1364, 2024 01 16.
Artigo em Inglês | MEDLINE | ID: mdl-38228671

RESUMO

To explore the psychological experience and emotional needs of returning to family and society after treatment in an adolescent with cancer. A phenomenological research design was employed to conduct a semi-structured interview with nine cancer adolescents in the convalescence stage. Colaizzi's seven-step analysis was used for the data analysis. Three themes of the psychological experience of an adolescent with cancer in convalescence were summarized: continuous negative emotions, emotionally intense behavior, and discomfort of returning to society. The psychological experience of an adolescent with cancer in convalescence returning to family and community is sensitive and complex. Medical staff, families, and schools should provide personalized care according to their different psychological characteristics and emotional needs so that they can return to family and society smoothly.


Assuntos
Saúde Mental , Neoplasias , Humanos , Adolescente , Adaptação Psicológica , Convalescença , Neoplasias/terapia , Neoplasias/psicologia , Pesquisa Qualitativa
4.
PLoS One ; 18(11): e0288379, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37992032

RESUMO

A large volume of evidence indicates that only high-class students attend extracurricular activities (Art, music, sport, dancing). On the other hand, this evidence intensively underlines the substantial importance of such extracurricular activities, particularly in visual art, in promoting children's cognitive and non-cognitive well-being. Adolescents' participation in visual art was always interrelated with enhancing their emotional affection towards the Art and cognitive skill in making one, which ultimately built solid efficacy that allows them to interact with their society. The present cross-sectional study sought to shed light on the potential impact of visual art on adolescents' emotional, cognition, and self-efficacy development, which needs to be improved in the Chinese context. Hence, randomly sampled (N = 2139) junior secondary school students were recruited from the rural province of Guizhou in Southwest China to attain the aim of the study. The study's finding affirms that students engaged in artistic activities start to develop a habit of communicating with their peers, showing their work, and commenting on works made by their peers or observed in art exhibitions or museums; such a process makes them self-efficacious. Ultimately, this paper extends the application of visual art activities from educational benefits to nonacademic development, which are the primary agents for children's well-being.


Assuntos
Arte , Música , Criança , Humanos , Adolescente , Estudos Transversais , Cognição , Emoções
5.
Front Psychol ; 14: 1153866, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37691814

RESUMO

Background: Jealousy is a complex emotion and can be healthy or pathological, depending on the intensity and the degree of control. Excessive jealousy was characterized by anxiety, anger, and alienation in the insecure attachment relationship. Objective: To explore how insecure attachment triggered this intense emotion, this study investigated the relationship between two insecure attachment dimensions and jealousy and explored the influence of self-differentiation on the relationship. Method: A total of 477 undergraduates participated in the study, and the Bringle self-report jealousy scale (BSJS), the relationship questionnaire (RQ), the intimate relationship experience questionnaire (ECR), and the revised edition of self-the differentiation questionnaire (DSR) were used. Result: The results showed that: (1) attachment anxiety had a significant positive predictive effect on jealousy, but attachment avoidance had no significant positive predictive effect; (2) self-differentiation partially mediated the relationship between attachment anxiety and jealousy, but it has no significant mediating effect between attachment avoidance and jealousy. Conclusion: The results suggest that attachment anxiety was correlated with jealousy because it strengthened the intensity of anxiety and anger toward their attachment figures and became out of control through a lower level of self-differentiation, which has important implications for clinical intervention.

6.
PLoS One ; 18(5): e0285439, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37253030

RESUMO

Ethiopia and China share a common educational agenda in cultivating and obtaining competent vocational graduates who fulfill the need of the modern, technologically advanced industrial workplace. Unlike most evidence, the present study adopted Self-determination Theory to understand Ethiopian and Chinese higher Vocational education and Training (VET) college students' learning motivation. Hence, this study recruited and interviewed 10 volunteers senior higher VET students from each setting to unfold their satisfaction with psychological needs. The study's main finding affirms that although both groups felt the autonomy of choosing the vocational field they sought to master, their learning process was submissive to their henpecked teaching method, which ultimately restrained the participants' feeling of competence for being enclosed in less practical training space. As per the study findings, we forward feasible policy and practical implications suggested for meeting the motivational needs of VET students and promoting learning stability.


Assuntos
Motivação , Educação Vocacional , Adolescente , Humanos , População do Leste Asiático , Aprendizagem , Autonomia Pessoal , Estudantes/psicologia
7.
PLoS One ; 18(5): e0285843, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37228082

RESUMO

Higher education around the globe is striving to develop rigor and productive doctoral studies that mainly evolve in fostering doctoral students' research skills by furnishing the necessary socialization process which predicts their future professional and academic decisions. Although scholars investigated the socialization experiences of doctoral students from different perspectives and stages, a large body of evidence is concentrated in western countries that do not define or imply non-western countries like Pakistan. Therefore, the present qualitative study sought to be an icebreaker and stimulant investigation to unfold doctoral students' socialization experience in research-intensive universities through the lens of Weidman's socialization framework. After interviewing 24 doctoral students, the findings revealed that doctoral students have high expectations from research universities to enhance their research capabilities. Moreover, most students knew the research's significance for personal and professional development. The study concluded the progressive and adverse research socialization experiences of doctoral students.


Assuntos
Docentes , Socialização , Humanos , Estudantes , Pesquisa Qualitativa , Universidades
8.
Front Psychol ; 13: 1056715, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36506996

RESUMO

[This corrects the article DOI: 10.3389/fpsyg.2022.987644.].

9.
Front Psychol ; 13: 987644, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36186354

RESUMO

Unlike in Western countries, scholars and the Chinese government pay less attention to the role of extracurricular activities (ECAs) in fostering children's cognitive and non-cognitive well-being. Accordingly, essential ECAs such as visual arts programs are serviced by expensive privately owned schools, creating social injustice. The primary aim of the current study is to examine whether children benefit from ECAs if parental support and guidance for managing time spent on ECAs and academics exist based on the threshold model. The study comprised over 2,400 primary school students in one Chinese province and considered the SES of the area. Surprisingly, the present study's findings illustrate that contemporary Chinese parents differ from traditionally aggressive and overbearing parents who do not value their children's interests. However, the current study finding suggested that children's participation in out-of-school visual art activities doesn't have a substantial value in promoting children's academic performance in the face of genuine interest and supportive parenting, which negates the threshold model.

10.
Children (Basel) ; 9(9)2022 Aug 29.
Artigo em Inglês | MEDLINE | ID: mdl-36138627

RESUMO

PURPOSE OF THE STUDY: This study sought to explore the psychological well-being, academic adjustment, and quality of parental attachment of LBC during COVID-19 based on Left-Behind Children's (LBC) word of mouth. METHOD: In light of the abundance of quantitative studies, this qualitative study explored the psychological, academic, and parental attachment experiences of rural LBC during COVID-19. To this end, we conducted semi-structured interviews with 22 LBCs aged 10-15 in May 2021. RESULT: The study results reveal that LBCs developed severe psychological illnesses after the pandemic severely disrupted their already disturbed lives. Our findings showed that most LBCs feel they do not need their parents, which reflects their long record of hopelessness and agony regarding the absence of their parents. CONCLUSION: Although COVID-19 is a global problem, its impact was particularly devastating for LBCs who have nobody around who could help them with their academic, personal and social need. In the modern COVID-19 era, it seems that Chinese grandparenting has become unreliable in the face of radical change in contemporary Education, society, and the economic system. Therefore, this study suggests that the Chinese government should seek to identify and monitor these children by working with NGOs that target such children.

11.
BMC Public Health ; 22(1): 1018, 2022 05 20.
Artigo em Inglês | MEDLINE | ID: mdl-35596160

RESUMO

BACKGROUND: In light of the recent policy reform in China, the present study aims to investigate the potential impact of family SES on the quality of the parent-child relationship (PCR) through the serial mediating role of participation in organized visual art activities in privately owned centers (VAA1) and parent-supervised visual art activities (VAA2) across genders. METHOD: A cross-sectional study was conducted in anonymous province located in the southwestern part of China. A total of 1624 primary school students aged 7 to 14 years were recruited through a random sampling technique. Subsequently, anonymous survey responses were taken from all students. Multiple serial mediation analysis was performed by using AMOS 21.0 software to attain the primary aim of the study. RESULT: According to the total sample model result, SES has a significant direct effect on the parent-child relationship (ß = 0.47, p < 0.001), children's participation in VAA1 (ß = 0.197, p < 0.001) and VAA2 (ß = 0.269, p < 0.001). Moreover, the mediation model result indicates that SES has a stronger indirect effect on the parent-child relationship through a mediating role of VAA1 (ßgirl = 0.08, p < 0.01; ßboys = 0.04, p < 0.01) for female than male samples. However, the mediating effect of VVA2 between SES and the parent-child relationship in the female (ß = 0.08, p < 0.001) and male (ß = 0.08, p < 0.01) models is equal, although female gender is highly significant. Ultimately, the serial mediation analysis result affirms that the serially mediating role of VAA1 and VAA2 between SES and the parent-child relationship was equal across genders (ßboys = 0.001, p < 0.001; ßgirls = 0.001, p < 0.001). CONCLUSION: Unlike previous studies, this study's multigroup model shows that both male and female children can equally restore their relationship with their parents by having substantial participation in both VAA1 and VAA2. Thus, parents ought to play the main role in facilitating and supporting children's visual art activities without parenting that shows a gender bias.


Assuntos
Relações Pais-Filho , Sexismo , Adolescente , China , Estudos Transversais , Feminino , Humanos , Masculino , Pais , Classe Social
12.
Child Indic Res ; 15(5): 1719-1740, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35251364

RESUMO

COVID-19 has had considerable effects on people's lives worldwide, particularly left-behind children in China as they tragically witnessed the outbreak. From the outset, millions of left-behind children in rural areas experienced extensive physical and psychological disturbances because their migrant parents who lived in the city or another province could not be with them. This study explored the psychological, academic, and physical well-being of rural left-behind children during COVID-19. We captured the experiences of 10- to 15-year-old children and adolescents who were left behind by their migrant parents before the COVID-19 outbreak. The results of the present study suggest that left-behind children have exhibited severe psychological illnesses since the pandemic has limited their social interactions with peers and increased improper caretaking from grandparents.

13.
BMC Infect Dis ; 18(1): 596, 2018 Nov 26.
Artigo em Inglês | MEDLINE | ID: mdl-30477441

RESUMO

BACKGROUND: Chlamydia trachomatis is the most common curable sexual transmitted bacterial infection in the world, including Sub-Saharan Africa. There is nil systematic review and meta-analysis on Chlamydia trachomatis infection in Sub-Saharan Africa among reproductive age women. Therefore, this study was carried out to determine the pooled prevalence of chlamydia trachomatis infection in Sub-Saharan Africa among reproductive age women. METHODS: A comprehensive literature search was conducted from biomedical data bases: Medline, PubMed, EMBASE, Google scholar, HINARI and Cochrane Library using a special index search terms (medical subject headings (MeSH), title and abstract. The Cochrane Q test and I2 statistics was used to test heterogeneity and publication bias was assessed using Begg's and Egger's tests. Results were presented in tables, figures and funnel plot. Data were pooled in a meta-analysis using a random effects model. RESULTS: Twenty-four studies were included in this meta-analysis. There was a high level of heterogeneity among studies. The pooled prevalence of Chlamydia trachomatis infection in Sub-Saharan Africa among reproductive age women was 7.8% (95% CI: 5.6-10.6). CONCLUSION: This review showed that Chlamydia trachomatis infection is high in Sub-Saharan Africa among reproductive age group women. This evidence suggests that governmental and non-governmental organization shall give attention for primary prevention of this infection. Likewise, in resource limited countries policy makers, stakeholders and health care providers' due attention for Chlamydia trachomatis specific and rapid diagnostic test, treatment in any medical out and in patient clinics for reproductive age women.


Assuntos
Infecções por Chlamydia/epidemiologia , Chlamydia trachomatis , Infecções Oportunistas Relacionadas com a AIDS/epidemiologia , Adulto , África Subsaariana/epidemiologia , Feminino , Humanos , Adulto Jovem
14.
BMC Res Notes ; 11(1): 605, 2018 Aug 22.
Artigo em Inglês | MEDLINE | ID: mdl-30134970

RESUMO

OBJECTIVE: Although typhoid fever is a major public health problem in Ethiopia, data is not available in the study area. Therefore, this study aimed to determine the prevalence, clinical presentation at the time of diagnosis and associated factors of typhoid fever among febrile patients visiting Shashemene Referral Hospital, southern Ethiopia. A cross-sectional study was conducted from January 1, 2016, to October 30, 2016. Socio-demographic and clinical data were collected using a structured questionnaire. A blood sample was collected and inoculated into Tryptic soy broth. RESULTS: A total of 421 adult febrile patients suspected of typhoid fever were included in the study. Of these, the overall prevalence of culture-confirmed typhoid fever was 5.0% (21/421). The prevalence of typhoid fever was significantly associated with rural residence (8.4%). As compared to the urban resident, the rural resident was 3.6 times more likely found to have culture-confirmed typhoid fever. The prevalence of typhoid fever was significantly associated with those patients whose water source was spring 7 (12.3%) and river 7 (13.2%). All of those study participants who used treated water were culture negative. Fever for ≥ 5 days, abdominal pain, and skin rash independently predicted blood culture-confirmed typhoid fever.


Assuntos
Febre Tifoide/diagnóstico , Adolescente , Adulto , Estudos Transversais , Etiópia/epidemiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Encaminhamento e Consulta , Salmonella typhi , Febre Tifoide/complicações , Febre Tifoide/epidemiologia , Adulto Jovem
15.
HIV AIDS (Auckl) ; 9: 203-210, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-29238229

RESUMO

INTRODUCTION: Hepatitis B virus (HBV) and hepatitis C virus (HCV) are hepatotropic viruses of public health significance worldwide. Despite their severe clinical impact in HIV-infected patients, there is inadequate information regarding the epidemiology of hepatitis/HIV coinfections in Ethiopia. Thus, this study aimed to determine the prevalence of HBV and HCV infections among HIV-infected patients at a tertiary hospital in Southern Ethiopia. METHODS: Stored sera, which were originally collected for the investigation of syphilis among HIV-infected clients, were analyzed in this study. Samples were tested for hepatitis B surface antigen (HBsAg) and antibody to hepatitis B core antigen using rapid diagnostic tests. Those samples that tested positive for HBsAg were further analyzed for hepatitis B e antigen. All sera were tested for antibody to HCV infection using rapid diagnostic test. RESULTS: HBsAg was positive for 6.3% of the participants; of whom, 10% were positive for hepatitis B e antigen. The exposure rates to HBV (antibody to hepatitis B core antigen) and HCV (anti-HCV) infections were 22.4 and 3.1%, respectively. The rates of coinfections with HBV-syphilis, HCV-syphilis, and HBV-HCV were found to be 3.1, 0.6, and 1.3%, respectively. HBV exposure rate was significantly higher among participants in the age range 40-49 years (adjusted odds ratio [AOR], 1.98; 95% CI, 1.01-3.88) and those who had a CD4+ T cell count <200 cells/µL (AOR, 2.40; 95% CI, 1.13-5.10) and 200-349 cells/µL (AOR, 2.36; 95% CI, 1.28-4.35). CONCLUSION: The rates of HBV and HCV infections were found to be similar to other subpopulations in Ethiopia. Age and CD4+ T cell level influenced the rate of HBV exposure. As human immunodeficiency virus-hepatitis coinfections are clinically consequential in people living with human immunodeficiency virus/acquired immunodeficiency syndrome, the need to screen this population for HBV and HCV infections is critically important.

16.
PLoS One ; 11(12): e0168580, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-28006003

RESUMO

BACKGROUND: Urogenital infection with Chlamydia trachomatis(CT) is one of the most common bacterial sexually transmitted infections (STIs) world-wide, especially in developing nations where routine laboratory diagnosis is unavailable. Little is known about the epidemiology of this infection in Ethiopia where other STIs are prevalent. This study was conducted to determine the prevalence and associated factors of CT infection among women of reproductive age. METHODS: A cross-sectional study was conducted among 322 consecutive women aged between 15-49 years at Hawassa University Referral Hospital from November 2014 to April 2015. Data on socio-demography and potential risk factors for genital infection were collected using structured questionnaires. Moreover, endocervical swabs were collected from all participants, screened for CT antigen using rapid immunochromatography assay, and cultured following the standard bacteriological method to isolate Neisseria gonorrhoeae. RESULT: In this study, the overall prevalence of CT antigen and N. gonorrhoeae infection was 61(18.9%) and 1(0.31%), respectively. Women aged 15-24 years had the highest prevalence of CT infection (24.2%), followed by those aged 25-34 years (16.8%) and those aged 35-49 years (9.6%). CTinfection was associated with women who had unprotected sex within the last six months (aOR = 3.459; 95% CI = 1.459-8.222) and were sexually active for 6-10 years (aOR = 3.076; 95% CI = 1.152-8.209). None of the clinical symptoms and diagnoses was significantly associated with CT antigen positivity. CONCLUSIONS: The high prevalence of genital CT infection in this study highlights the need for further large-scale studies on the general population. Thus, screening of women regardless of their symptoms should be in place.


Assuntos
Infecções por Chlamydia/epidemiologia , Chlamydia trachomatis/isolamento & purificação , Gonorreia/epidemiologia , Programas de Rastreamento , Neisseria gonorrhoeae/isolamento & purificação , Infecções Sexualmente Transmissíveis/epidemiologia , Adolescente , Adulto , Infecções por Chlamydia/microbiologia , Estudos Transversais , Etiópia/epidemiologia , Feminino , Gonorreia/microbiologia , Hospitais Universitários , Humanos , Pessoa de Meia-Idade , Prevalência , Encaminhamento e Consulta , Reprodução , Fatores de Risco , Infecções Sexualmente Transmissíveis/microbiologia , Adulto Jovem
17.
Rev Inst Med Trop Sao Paulo ; 58: 59, 2016 Sep 22.
Artigo em Inglês | MEDLINE | ID: mdl-27680164

RESUMO

Rapid diagnostic tests (RDTs) capable of detecting and differentiating Plasmodium species are needed in areas in which microscopy is unsuitable. This study was conducted to assess the diagnostic performance of the rapid test kit - SD BIOLINE Malaria Ag Pf/Pan(r) (05FK60) in an endemic area. Microscopy of Giemsa-stained blood films were performed to detect and estimate the Plasmodium density in malaria suspected patients. The performance of the SD BIOLINE Malaria Ag Pf/Pan test was evaluated using 272 Plasmodium-positive and 102 negative blood samples. The overall sensitivity of the SD BIOLINE Malaria Ag Pf/Pan test was 99.5% for P. falciparum and 92.6% for non-P. falciparum malaria infections. The respective specificity, PPV, and NPV of the test were 98.0, 98.4, and 99.0% for the diagnosis of P. falciparum, and 100.0 %, 100.0%, and 94.4% for non-P. falciparum species. The SD BIOLINE Malaria Ag Pf/Pan test showed an excellent performance in diagnosing Plasmodium infections in an endemic setting. Therefore, this point-of-care test could be used as an alternative to microscopy in places where P. falciparum is endemic and microscopy is unsuitable.

18.
Epidemiol Health ; 38: e2016001, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-26797221

RESUMO

OBJECTIVES: The aim of this study was to assess the rate of and risk factors for exposure to hepatitis B virus (HBV) and hepatitis C virus (HCV) among medical waste handlers. METHODS: A cross-sectional study was conducted from December 2014 to January 2015. A total of 152 medical waste handlers (MWH) and 82 non-medical waste handlers (NMWH) were studied. Serum samples were collected from participants and screened for hepatitis B surface antigen (HBsAg), hepatitis B core antibody (anti-HBc) and anti-HCV using rapid immunochromatography assay. MWH were also screened for hepatitis B surface antibody (anti-HBs). RESULTS: The respective prevalence of HBsAg, anti-HBc and anti-HCV was 1.3%, 39.4%, and 0.7% in MWH, compared to 2.4%, 17.1%, and 1.2%, respectively, in NMWH. Among MWH, 58.6% were susceptible to HBV infection. There was a significant difference in the rate of lifetime exposure to HBV in MWH compared with NMWH (odds ratio [OR], 3.17; 95% confidence interval [CI], 1.64 to 6.13). However, there was no significant difference between participant groups with respect to current HBV infection (OR, 0.53; 95%CI, 0.07 to 3.86) or anti-HCV (OR, 0.54; 95%CI, 0.03 to 8.69). Age older than 40 years and working in a hospital laundry were independent predictors of lifetime exposure to HBV infection. Eleven (7.2%) respondents were vaccinated against HBV. CONCLUSIONS: Lifetime exposure to HBV infection was significantly higher in MWH than in NMWH. The majority of MWH was not vaccinated against HBV and thus remains susceptible to contracting the infection. Screening upon hire followed by vaccination of MWH is recommended to reduce the transmission of HBV.


Assuntos
Pessoal de Saúde/estatística & dados numéricos , Hepatite B/epidemiologia , Hepatite C/epidemiologia , Resíduos de Serviços de Saúde/estatística & dados numéricos , Doenças Profissionais/epidemiologia , Exposição Ocupacional/efeitos adversos , Adolescente , Adulto , Estudos Transversais , Etiópia/epidemiologia , Feminino , Hepatite B/diagnóstico , Hepatite B/virologia , Anticorpos Anti-Hepatite B/sangue , Antígenos de Superfície da Hepatite B/sangue , Hepatite C/diagnóstico , Hepatite C/virologia , Anticorpos Anti-Hepatite C/sangue , Hospitais Públicos/estatística & dados numéricos , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Profissionais/diagnóstico , Doenças Profissionais/virologia , Prevalência , Adulto Jovem
19.
BMC Infect Dis ; 15: 189, 2015 Apr 17.
Artigo em Inglês | MEDLINE | ID: mdl-25884178

RESUMO

BACKGROUND: Syphilis facilitates both HIV (human immunodeficiency virus) transmission and acquisition, reflecting the complex interplay between the two infections. Scarce information exists regarding syphilis epidemiology in Ethiopian context. Thus, this study determined the sero-prevalence of syphilis and associated risk factors in people with HIV infection. METHODS: A cross-sectional study was conducted at Hawassa Referral Hospital, southern Ethiopia from January to May, 2014. A consecutive 993 HIV-infected participants were studied; but individuals under 15 years of age or treated for syphilis or those with a CD4+ T-cell count below 50 cells/µl were excluded. Structured questionnaires were used to collect data on socio-demography and potential risk factors for syphilis. Moreover, blood samples were collected from all participants and screened for syphilis using rapid plasma reagin (RPR) test, and those found sero-positive were confirmed using treponema pallidum haemagglutination assay (TPHA). RESULTS: The sero-prevalence of syphilis was found to be 7.3% (95% CI 5.7- 9%). The rate of infection was significantly higher among participants who were ART (antiretroviral therapy) naive (odds ratio (OR) = 2.2; 95% CI 1.22 - 4.1), men (OR = 2.2; 95% CI 1.22 - 3.87), older than 50 years of age (OR = 3.9; 95% CI 1.45 - 6.94), had only primary school level education (OR = 7.8; 95% CI 2.63 - 23.2) and had a history of blood transfusion (OR = 3.9; 95% CI 1.5 - 10.4). CONCLUSION: The high prevalence of syphilis among HIV-infected population warrants integrating syphilis screening with HIV care to limit the clinical consequences of untreated syphilis as well as its adverse impact on HIV transmission.


Assuntos
Infecções por HIV/complicações , Sífilis/epidemiologia , Adulto , Fatores Etários , Estudos Transversais , Etiópia/epidemiologia , Feminino , Humanos , Masculino , Programas de Rastreamento , Pessoa de Meia-Idade , Prevalência , Fatores de Risco , Estudos Soroepidemiológicos , Fatores Sexuais , Sífilis/sangue , Sífilis/complicações , Sorodiagnóstico da Sífilis
20.
BMJ Open ; 5(4): e007371, 2015 Apr 23.
Artigo em Inglês | MEDLINE | ID: mdl-25908677

RESUMO

OBJECTIVE: To determine the diagnostic performance of the SD BIOLINE HIV/syphilis Duo rapid test. DESIGN: A hospital-based cross-sectional study. SETTING: This evaluation was conducted at one of the largest hospitals in southern Ethiopia. PARTICIPANTS: Serum samples obtained from clients attending the antiretroviral therapy and voluntary counselling and testing centres were used. Sera were originally collected for the purpose of investigating syphilis epidemiology. The performance of the test to detect HIV was evaluated using 400 sera (200 HIV positives and 200 HIV negatives). Also, its performance to detect syphilis was evaluated using 85 syphilis positive and 100 syphilis negative serum samples. Individuals <15 years of age or syphilis treated or those with ≤50 cells/µL CD4 cell count were originally excluded. OUTCOME MEASURES: HIV screening was carried out according to the national rapid diagnostic testing (RDT) algorithm: Shenghai Kehua Bioengineering (KHB) test kit as a screening test, followed by the HIV1/2 STAT-PAK assay if positive. Where the result of the STAT-PAK is discordant with KHB, Unigold HIV is used as a tiebreaker to determine the result. We also used ELISA to resolve discordant HIV results. Syphilis serostatus was determined using the Treponema pallidum haemagglutination assay (TPHA). RESULTS: The respective sensitivity, specificity, positive predictive value and negative predictive value of the SD BIOLINE HIV/syphilis Duo test were 100, 99.5, 99.5 and 100% for HIV and 97.6, 96, 95.4 and 98% for syphilis testing, respectively. In reference to TPHA, the test kit reported 4 false positives and 2 false negative results for syphilis. The κ values were 0.99 for HIV testing and 0.94 for syphilis testing. CONCLUSIONS: The excellent performance of the SD BIOLINE HIV/syphilis Duo test to detect HIV as well as syphilis facilitates the integration of syphilis testing and treatment to the already established HIV prevention programme, ultimately contributing to the dual HIV and syphilis elimination goal.


Assuntos
Sorodiagnóstico da AIDS , Anticorpos Antivirais/sangue , Antígenos de Bactérias/sangue , Infecções por HIV/diagnóstico , Sorodiagnóstico da Sífilis , Sífilis/diagnóstico , Sorodiagnóstico da AIDS/instrumentação , Adolescente , Adulto , Idoso , Biomarcadores/sangue , Estudos Transversais , Etiópia , Feminino , HIV/imunologia , Infecções por HIV/sangue , Infecções por HIV/imunologia , Testes de Hemaglutinação , Humanos , Masculino , Programas de Rastreamento , Pessoa de Meia-Idade , Valor Preditivo dos Testes , Kit de Reagentes para Diagnóstico/normas , Sensibilidade e Especificidade , Sífilis/sangue , Sífilis/imunologia , Sorodiagnóstico da Sífilis/instrumentação , Treponema pallidum/imunologia , Adulto Jovem
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